Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis

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Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis

An 80-year-old woman presented with simultaneous increasing muscle weakness and nephrotic syndrome. A renal biopsy confirmed focal segmental glomerulosclerosis (FSGS). Her neurological diagnosis best fitted with a Guillain-Barre-like syndrome. There have been several cases of FSGS in combination with both conventional and atypical Guillain-Barre syndrome (GBS). Our patient was treated with high...

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Antiphospholipid syndrome (APS) is a clinicopathological syndrome characterized by the association of venous and/or arterial thrombo-embolic events, pregnancy morbidity and the presence of circulating antiphospholipid (APL) antibodies, namely lupus anticoagulant (LA) and/or anticardiolipin antibodies (ACLs). The diagnosis of definite APS is made when the patient fulfils one clinical (thrombosis...

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Focal Segmental Glomerulosclerosis.

Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant-important disease characteristics. In contrast, adaptive FSGS is associated with excessive nephron workload due to increased body size, reduced nephron ...

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Idiopathic focal segmental glomerulosclerosis.

Idiopathic focal segmental glomerulosclerosis (FSGS) is a primary glomerular disease that essentially represents a form of chronic, progressive renal fibrosis for which there is no discernible cause. Often presenting with or eventually manifesting the nephrotic syndrome, this disease is increasing in incidence in both children and adults. Therapy continues to be a challenge, although some patie...

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Collapsing Focal Segmental Glomerulosclerosis

Background and objectives: Treatment with IFN is rarely associated with nephrotic syndrome and renal biopsy findings of minimal-change disease or FSGS. Design, setting, participants, & measurements: We report 11 cases of collapsing FSGS that developed during treatment with IFN and improved after discontinuation of therapy. Results: The cohort consists of seven women and four men with a mean age...

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ژورنال

عنوان ژورنال: Clinical Kidney Journal

سال: 2013

ISSN: 2048-8505,2048-8513

DOI: 10.1093/ckj/sft104